![]() Prevention of both hypoprothrombinemia and hemorrhagic disease of the newborn. Vitamin K, commonly in the form of phytonadione, is frequently used in the treatment and ![]() A deficiency of vitamin K results in symptoms of abnormal bleeding, including epistaxis, hematuria, ecchymoses, and bleedingįrom the gastrointestinal tract. Vitamin K 1 (phylloquinone or phytonadione) is found in plants and Vitamin K 2 (a menaquinone) is synthesized by Gram positive bacteria found in normal intestinal flora. Vitamin K is an essential cofactor for several clotting factors and anticoagulant proteins. With a discussion of the pathogenesis pathogenesis of vitamin K 1 and available treatment for this condition. The history and clinical presentation of our case is presented We present a case of a localized cutaneous reaction to intramuscular vitamin K 1 in a peripartum patient with acute fatty liver of pregnancy. Erythematous, indurated, pruritic plaques uncommonly occur in adults after intramuscular Vitamin K 1 is frequently used in the treatment and prevention of hypoprothrombinemia and hemorrhagic disease of the newborn. Department of Dermatology, University of Texas Medical Branch, Galveston, Texas. ![]() School of Medicine, University of Texas Medical Branch, Galveston, Texasģ. Department of Dermatology, Case Western Reserve-Metro Health Center, Cleveland, OhioĢ. Tatiana Sousa MD 1, Lindsey Hunter BS 2, Matthew Petitt DO 3, Michael George Wilkerson MD 3 Dermatology Online Journal 16 (12): 16 1. Letter: Localized cutaneous reaction to intramuscular vitamin K in a patient with acute fatty liver of pregnancy
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